Fatigue and mild anemia can often improve with treatment, but nerve-related symptoms deserve special attention. Tingling, numbness, balance problems, memory changes, and walking difficulty can sometimes become serious if deficiency is left untreated.
NICE guidance advises not delaying B12 replacement while waiting for test results in people with suspected megaloblastic anemia and neurological symptoms, especially when symptoms may suggest spinal cord involvement.
This does not mean you should self-treat with high-dose supplements without guidance. It means neurological symptoms should be taken seriously and evaluated promptly.
How Is Vitamin B12 Deficiency Diagnosed?